ABSTRACT
Introduction In order to evaluate the risks to human health from exposure to detergents and detergent ingredients, toxicity and exposure must be evaluated. Overall, there are standard tests and approaches for evaluating toxicity of certain new ingredients and product formulations. However, for certain immunologic endpoints, such as an antibody-mediated allergy, there are no standard approaches that can be used by the industry, including valid Organization for Economic Cooperation and Development (OECD) models or valid in vitro methods.
