ABSTRACT
IARC MONOGRAPH 10 1976 DAUMOMYCIN IS CARCINOGENIC IN RATS FOLLOWING IV INJECTION OF SINGLE DOSES AND IN MICE FOLLOWING ITS REPEATED SC INJECTION. IT PRODUCED MAMMARY AND KIDNEY TUMORS IN RATS AND LOCAL SARCOMAS IN MICE. IN A 1979 SUPPLEMENT, IARC DETERMINED THAT THERE IS SUFFICIENT EVIDENCE FOR THE CARCINOGENICITY OF DAUNOMYCIN IN ANIMALS.
