ABSTRACT
NCI CARC TRS 7 DHEW PUB NO NIH 77-807 TUMORS APPEARING IN TREATED RATS AND MICE WERE SIMILAR IN TYPE AND NUMBER TO THOSE IN CONTROLS, AND NO PATHOLOGIC OR STATISTICAL EVIDENCE OF INDUCTION OF TUMORS IN THESE SPECIES BY PHENFORMIN WAS FOUND (FEEDING STUDY). HYPOGLYCEMIC DRUGS
REPORT 01
REPORT 06
REPT'D USE
CAS NO
IARC MONOGRAPH 12 1976 PHENICARBAZIDE IS CARCINOGENIC IN MICE WHEN ADMINISTERED ORALLY, THE ONLY SPECIES AND ROUTE INVESTIGATED. IT PRODUCED LUNG TUMORS AND ANGIOMAS AND/OR ANGIOSARCOMAS IN THE LIVER. MULTI-AGENCY CROSS CHECK N HHS MAGUIRE YOSHA CARC N EPA CAG N EPA RCRA N EPA CLEAN AIR N EPA CLEAN WATER EXPERIMENTAL ANTIPYRETIC/NEUROLEPTIC AGENT
REPORT 01
REPORT 02
REPT'D USE
IARC MONOGRAPH 13 1977 PHENOBARBITAL SODIUM IS CARCINOGENIC IN MICE AND RATS AFTER ITS ORAL ADMINISTRATION FOR LIFETIME. IN MICE, IT PRODUCED BENIGN AND MALIGNANT LIVER-CELL TUMORS; IN RATS, BENIGN LIVER-CELL TUMORS WERE OBSERVED VERY LATE IN LIFE.
