ABSTRACT
The developments of the Lewis base-modified zirconia and mixed-oxide containing zirconia as stationary phases for high-performance liquid chromatography (HPLC) are reviewed. In this context, the preparation methods of porous spherical zirconia, and zirconia supports for HPLC based on modification with fluoride, phosphate, phosphonate, carboxylic acid, phenols, and protein, as well as cyclodextrin derivative, are covered. The application of modified-zirconia in capillary electrochromatography (CEC) is also discussed.
