ABSTRACT
Perhaps the most important and pertinent studies are those of the large populations of newborns screened in Sweden [200,000 by Sveger (60)] and in Oregon [107,000 by Buist et al. (61) and Wall et al. (62)]. At age 8, 13 or 8% of the ZZ or SZ subjects, respectively, had asthma in the Swedish study (63). This may be high, since only 2.4% of 8-year-old Swedish children were reported to have asthma in a separate study (64). Studied from ages 3 to 7, 19 ZZ and SZ subjects showed no evidence of OAD in the Oregon Group (61). Later the Oregon group reported that of 22 ZZ and SZ subjects studied in adolescence, only two siblings had mild reversible asthma (62).
