ABSTRACT
In keeping with the “unifying theory”, presented by Gorlin et al 1986, C H D has a common etiopathogenetic denominator, i.e., rupture o f an atherosclerotic plaque and consequent thrombosis and/or microembolization and/or spasm. These induce unstable angina, myo cardial infarction and sudden death, all included amongst the “acute coronary syndromes”. Thus plaque rupture becomes the center of the CH D universe, with rupture proposed to occur even in small, angiographically undetected plaques (Ambrose et al, 1988). Its prevention, and that alone, will resolve the C H D problem.
