ABSTRACT

Introduction Myelodysplastic syndromes (MDSs) are clonal disorders of hematopoietic

cells that are manifested in the peripheral blood (PB) by cytopenias and clinically by the symptoms resulting from cytopenias or from blood cell dysfunction. The classic triad for diagnosing MDS is:

• PB cytopenia(s) • Dysplasia in one or more cell line • Bone marrow (BM) hypercellularity

MDS is most commonly identified in BM specimens performed to evaluate anemia in elderly patients.