ABSTRACT
Botulinum toxin is the most potent neurotoxin known to man. It is produced by the anaerobic bacteria Clostridium botulinum . In the early nineteenth century, it was responsible for large outbreaks ofbotulism, a systemic food poisoning. In the twentieth century, botulinum toxin has developed from man s most powerful poison into a tool used to treat in a variety of disorders. In the early 21st century the understanding and clinical applications of botulinum toxin have exploded. It s indications now span a wide range of medical and surgical specialties.
