ABSTRACT
This chapter provides that the themed presentation encourages quick, focused study and detailed answers aid comprehension and encourages familiarity with each topic with essential diagrams, colour images and sample MRIs. Vitamin B12 deficiency can cause subacute combined degeneration of the cord; this affects the dorsal columns that carry proprioception and vibration. Friedreich’s ataxia affects the young. Paraneoplastic cerebellar degeneration is an autoimmune disease where antibodies are directed against Purkinje cells in the cerebellum. It is often associated with lung, breast and ovarian cancers and Hodgkin’s lymphoma. Patients commonly present with cerebellar signs. They can also have foot deformities (high-arched feet or pes cavus), diabetes mellitus and hypertrophic cardiomyopathy (a usual cause of death in these patients).
