ABSTRACT

OH

OMe

N

N N

O

O H

Me

C23H23N5O4 433.466

Extensive tautomerism possible in all Naamidines. Alkaloid from the Red Sea sponge Leucetta chagosensis and from Notodoris citrina. Antagonist of the epidermal growth factor receptor. Yellow foaming oil. Sol. MeOH, CHCl3; poorly sol. H2O. lmax 240 (e 1160); 281 (e 4330); 366 (e 10500); 392 (e 13500); 416 (e 10700) (CHCl3) (Derep). lmax 225 (e 21400); 276 (e 4800); 384 (e 10060) (MeOH) (Berdy).