ABSTRACT

Transplantation is the replacement of an organ or other tissue, such as bone marrow, with organs or tissues derived ordinarily from a nonself source such as an allogeneic donor. Organs include kidney, liver, heart, lung, pancreas (including pancreatic islets), intestine, or skin. In addition, bone matrix and cardiac valves have been transplanted. Bone marrow transplants are given for nonmalignant conditions such as aplastic anemia as well as to treat certain leukemias and other malignant diseases.