ABSTRACT

Introduction 407

Chemistry 408

Biology 408

Mechanism of Action 410

Clinical Studies 410

Conclusion 411

References 411

INTRODUCTION

The success of retinoids and hydroxy acids as active ingredients in skin care pro-

ducts designed to improve the appearance of aging skin, has stimulated the search

for additional compounds. The use of both retinoids and hydroxy acids may be

associated with skin irritation, further stimulating interest in alternatives. A

recent addition to this armamentarium is kinetin (N6-furfuryladenine). Kinetin

is a plant hormone known for growth-promoting and anti-aging effects in

plants. It has been incorporated into several cosmeceuticals prompting a more

detailed review.