ABSTRACT
Introduction 550
Molecular Biology 550
Absorption and Transport 550
Metabolism and Excretion 550
Molecular Pharmacology 551
Copperceuticals and Skin: The GHK-Cu Tripeptide 552
GHK-Cu Analogs 552
The Importance of the Copper Peptide Complex 554
Skin Penetration Study of GHK-Cu 554
Immunohistological Assessment 555
Controlled Usage Study in Photodamaged Skin 555
Methods 556
Clinical Results 557
Viscoelastic Properties 558
Ultrasound Measurements 559
Digital Images 559
Safety of GHK-Cu Complex 559
Conclusions 561
References 561
INTRODUCTION
Copper peptide, a recent addition to the cosmeceutical pantheon, has an extensive
scientific background. This chapter focuses on cutaneous implications.