ABSTRACT
In living cells, many key events such as gene expression and protein-protein interactions follow from elementary reactions between the cellular consituents at the molecular level (e.g., genes, RNAs, proteins). There is considerable inherent randomness in the order and timing of these reactions. This randomness can be attributed to the random collisions among cellular constituents whose motion is induced by thermal energy and follows specific statistical distributions. The result is fluctuations in the molecular copy numbers of reaction products both among similar cells and within a single cell over time. These fluctuations (commonly referred to as cellular noise) can propagate downstream, impacting events and processes in accordance to the dynamics of the network interconnection.
