Multiscale Modeling Approach for Studying MDH-Catalyzed Methanol Oxidation

Biological processes can be considered as complex networked systems that involve events that occur on a variety of time and length scales ranging from nano-to mesoand even macro-scales, thus making these processes fundamental challenges to model. Multiscale modeling is an effective tool to deal with these complex biochemical processes by integrating various physical techniques ranging from atomistic to macroscopic simulations (Figure 5.1) [1]. Particular modeling techniques can be

5.1 Multiscale Modeling of Biological Systems ................................................... 91 5.2 Monte Carlo Modeling ...................................................................................93 5.3 Modeling of an Enzyme-Assisted Reaction ...................................................95 5.4 Methanol Dehydrogenase Enzyme .................................................................97