ABSTRACT

Biosensors are bioanalytical systems defined by their integration of appropriate levels of sample

handling, biotransduction, instrumentation, and information output. Such systems have as their

purpose the reporting of, through measurement or monitoring, the chemical potential energy of a

targeted analyte. The biosensor measures or monitors then generates analytically useful data in an

information context. Central to the biosensor system, and indeed defining over other bioanalytical

systems, is the use of a biotransducer. The biotransducer is a device that converts the concentration of

the target analyte into a proportionate measurable signal via an intimate combination of a biological

recognition system and a physicochemical transducer.