ABSTRACT
Today’s synthetic chemist is under increasing pressure to discover and deliver compounds quickly, with an eye on devising synthetic methodology that can be readily scaled to enable the next stage of development to be performed rapidly. While emerging technologies such as microwave chemistry, and combinatorial applications have over the decades been implemented within research laboratories, a bottleneck still remained at the scale-up step. Micro reaction technology attempts to solve the problem from the perspective of developing reaction methodology within the laboratory that can be used directly for the performance of reactions at a production-scale, thus driving down the timescales required to put compounds into production. This goal is achieved by basing the technique on the rapid generation of high-quality chemical information, which can be readily scaled once a compound of interest is identi ed.
