ABSTRACT
Osteoarthritis (OA) of the knee is the most common source of morbidity, disability, and loss of function in elderly people. Knee OA causes knee pain, which limits daily activities such as getting in and out of chairs, walking comfortably, climbing stairs, performing personal care and household tasks, shopping, and doing errands in people older than 65 years old [1]. The resulting inactivity leads to physical deconditioning and may play an indirect role in the development of common chronic comorbidities (obesity, hypertension, cardiovascular and respiratory diseases, diabetes, depression, etc.) [2]. The large number of patients with knee OA results in signi—cant health care expenditures [3, 4] and a socioeconomic burden [5] on society.
