ABSTRACT
Abstract .................................................................................................................. 119 6.1Introduction .................................................................................................. 120 6.2Properties of Phospholipids .......................................................................... 121
6.2.1Phospholipid Structure ..................................................................... 121 6.2.2Formation of Supported Lipid Films ................................................ 124
6.3 Interfacial Force Microscopy........................................................................ 126 6.4Experimental Details .................................................................................... 127 6.5Mechanical Properties .................................................................................. 128
6.5.1Normal Force Properties .................................................................. 128 6.5.1.1Supported Lipid Monolayers .............................................. 128 6.5.1.2 Supported Lipid Bilayers ................................................... 131
6.5.2Friction Force Properties .................................................................. 138 6.5.2.1Supported Lipid Monolayers .............................................. 138 6.5.2.2Supported Lipid Bilayers ................................................... 140
6.6Summary and Conclusions ........................................................................... 142 Acknowledgments .................................................................................................. 142 References .............................................................................................................. 143
mechanical properties of phospholipid monolayers and bilayers, we can correlatethe2Dstructureofthesesystemswiththeirnanoscalemechanicalbehavior.Bymeasuringtheelastic,plastic,andfrictionproperties,weobservethat theclosepackedgelphasesystemsbehavesimilartoa2Dsolid,whiledisordered‘uidphasesystemsresemblea2Dliquid.Relevanttotheirapplications in nanotechnology, these results provide a foundation for how supported lipid ”lms interact with objects in the ∼500 nm−1 μm size range.
