ABSTRACT
Transient receptor potential (TRP) family channels are conserved from Caenorhabditis elegans to humans. About 28 TRP members have been identi—ed in mammals. On the basis of their sequence homology and functional similarity, these channels are further divided into seven subfamilies. Accumulating evidence shows that mammalian TRP channels are broadly involved in regulating sensory physiology, as they are important for sensing a wide variety of physical and chemical cues from both intracellular and extracellular sides.1
