ABSTRACT
Diseases ............................................................................................248 10.1.2 Historical Overview of Inammatory Phenomena in
Neuropsychiatric Disorders ..............................................................249 10.1.3 Connections between Neuropsychiatric Disorders,
Somatic Disorders, and Inammation ..............................................249 10.1.3.1 Increased Rates of Psychiatric Disease in
Medically Ill Patients .........................................................249 10.1.3.2 Neuropsychiatric Disorders as Risk Factors for the
Development of Medical Illness ........................................250 10.2 Relationship of Inammation to Neuropsychiatric Disease: Mood and
Anxiety Disorders ......................................................................................... 251 10.2.1 Increased Inammation in Major Depression .................................. 251 10.2.2 Increased Inammation in Anxiety Disorders ................................. 252
10.2.2.1 Posttraumatic Stress Disorder ............................................ 253 10.3 Impact of Cytokines on the Brain ................................................................254