Natural Products as Inhibitors of Hypoxia-Inducible Factor-1

Activation of HIF-1 .............................................................................. 193 7.5 Agents That Promote HIF-1α Degradation .................................................. 194

7.5.1 Inhibitors of Mitochondrial ROS-Mediated HIF-1 Signaling ..........203 7.5.2 Other Agents That Promote HIF-1α Degradation ............................205