ABSTRACT

Starting point Event Endpoint Birth Death from any cause Duration of life Birth Incidence of disease Age at onset Diagnosis of disease Death from any cause Overall survival Diagnosis of disease Death from the disease Disease-specific survival Diagnosis of disease Progression of disease Time to progression Start of treatment Recurrence of disease or death Disease-free survival Admission to college Graduation Duration of study Surgery Recovery Time to recover

Generally speaking, this book will only study events that occur once. Events that could happen repeatedly are outside the scope of the book (see Hougaard (2000) and Cook & Lawless (2007) for comprehensive reviews). So, this book will cover models for the incidence of a chronic disease like cancer, but not for repeated incidence of recurrent diseases like influenza or the common cold.