ABSTRACT

The generic criteria for Madurella are primarily based on tissue morphology and overall sterility on mycological media, as well as an invasive potential in human and animal hosts. The genus is composed of two formally described species, namely, Madurella mycetomatis and Madurella grisea, plus a dozen poorly characterized species collectively named Madurella spp. [1]. M. mycetomatis is the generic type species. All Madurella species were isolated from cases of black-grain mycetoma [2]. Mycetoma is a chronic in¼ammatory disease, which remains localized, involves cutaneous and subcutaneous tissues, the fascia, and bones [3]. The disease is characterized by tumefaction, discharging sinuses, and the presence of fungal grains [3].