ABSTRACT
Mutagenicity or Genotoxicity ....................................................................... 258 16.5 A Mechanistic Understanding of The Antimutagenic or Antigenotoxic
Pro‹le of Phyllanthus Sp. ............................................................................. 259 16.6 Concluding Remarks .................................................................................... 261 References .............................................................................................................. 262
sodium azide are also of potential relevance. Ionizing radiations induce damage to DNA and other macromolecules and are known to be mutagenic or genotoxic. Over the past decades, considerable efforts have been made to identify plants or their constituents capable of attenuating mutagenesis or genotoxicity. One such notable herb is Phyllanthus, a large genus in the family Phyllanthaceae. Several species of this plant have been used to treat a wide number of diseases in many traditional systems of medicine in diverse geographical areas and are attributed with bene‹cial pharmacological effects.
