The word wine comes from the Latin “vinum,” meaning vigor and strength. “Vita vinum est,” life is wine, stated Gaius Petronious, a  rst-century Roman writer (~27-66 ad). Hippocrates (460-377 bc), known as the “Father of Medicine,” recommends wine, mixed with water “in equal parts.” Pasteur (1822-1895) called wine “the healthiest and most hygienic drink that man has produced.” In 1979, St. Leger et al. drew attention to the protective effects of wine against ischemic heart disease (St. Leger et al., 1979).