ABSTRACT
Since the early 1960s, antibodies have been used as an analytical reagent to capture a target molecule (antigen) from a sample forming an antibody-antigen complex also known as an immune complex that is then quantišed either directly or through the detection of a label (or reporter molecule)
9.1 Immunoassays....................................................................................................................... 243 9.1.1 Introduction .............................................................................................................. 243 9.1.2 Antibodies and Antigens ..........................................................................................244 9.1.3 Immunoassays...........................................................................................................245 9.1.4 Immunoassay Formats ..............................................................................................246 9.1.5 Use of Labels in Immunoassays ...............................................................................248 9.1.6 Use of Particles as Labels .........................................................................................248 9.1.7 Coupling Proteins to Particle Surfaces .....................................................................249
