ABSTRACT
Cyclodextrins (CDs) are a series of oligosaccharides Šrst found by Villiers in 1891 and thereafter were described in detail by Schardinger. CDs are produced by acting on starch with a speciŠc CD glucanotransferase (CGTase, EC 2.4.1.19) from Bacillus macerans [1]. In 1930s, Freudenberg and his coworkers revealed that the CD molecules were built from maltose units containing only α-1,4-glycosidic linkages, and they also postulated CDs as cyclic structure. Since 1950s, many scientists, especially the research group led by Szejtli, have paid great attention to the preparation methods, structure, and physicochemical properties of CDs; and their works showed CDs as promising molecules for industrial possibilities [1,2].
