ABSTRACT
First described in 1912 by Hakaru Hashimoto as “struma lymphomatosa,” this disease has been also called Hashimoto’s thyroiditis, chronic thyroiditis, lymphocytic thyroiditis, lymphadenoid goiter, and more recently chronic autoimmune thyroiditis (CAT), after its recognition as the original paradigm for organ-specic autoimmune diseases. CAT includes several variants (Table 4.1) sharing different proportions of common pathological features including diffuse lymphocytic inltration, brosis, atrophy, and oncocytic changes of follicular cells.
