ABSTRACT
DDS are polymeric or lipid carrier systems that transport drugs to their targets or receptor sites in a manner that provides their maximum therapeutic activity, prevents their degradation or inactivation during transit to the target site(s), and protects the body from adverse reactions due to inappropriate disposition. The goal of a drug delivery system is to release the drug(s) to simultaneously provide maximal safety, effectiveness, and reliability (Figure 12.1). Design of an effective delivery system requires a thorough understanding of the drug, the disease, and the target site. Various physicochemical product properties that in–uence the quality features of Plasma clearance kinetics, tissue distribution, metabolism, and cellular interactions of a drug can often be controlled by the use of a delivery system.
