ABSTRACT

Almost all the pharmaceutical dosage forms involve the handling of powders at one or more stages of their preparation. For example, the manufacture of tablets and capsules requires the compression or ­lling of powders in a tableting or a capsule ­lling machine, respectively. Most of the drugs are solid state at room temperature. Therefore, even the processing of liquid dosage forms, such as oral, ophthalmic, or parenteral solutions, requires the drug to be dissolved in a solvent during their manufacture.