ABSTRACT
Dosage forms that are in a plastic, malleable semisolid state at room temperature include ointments, creams, gels, pastes, lotions, jellies, and foams. These semisolid preparations may contain dissolved and/or suspended drugs. These preparations are designed to stay in physical contact with the surface of application for a reasonable duration of time, before they are inadvertently removed or washed off. Their semisolid state and plastic rheological behavior is designed to aid their application to the target surface as a lm.
