ABSTRACT

Regardless of the possible advantages of various sensing units based on DNA cholesteric liquid-crystalline dispersions (CLCD) or DNA nanoconstructions (NaC), the principal dif¤culty in the application of the “test-tube” form of such units is the insuf¤cient temporal stability of their optical properties. This instability is caused by the fact that at a long storage (longer than a week), as the result of the sedimentation and/or coalescence of CLCD particles or DNA NaC, their concentration in the solution is diminished. Such change in concentration results in an uncontrollable alteration of the optical signal generated by these nanoobjects.