ABSTRACT
Since the early investigations by Berthelot (1862) and N.A. Menshutkin (1887) the solvent effects on chemical reaction rate is the object of regard of chemists [1]. Primarily, solvents were considered as reaction media, and attempts were made to explain solvent effects by pure physical interactions [2, 3]. In recent decades, specific (chemical) interactions between solutes and the medium became of greater attention. Further on, the necessity of combined consideration of all solvation interactions in the solution was highly apprehended [4, 5]. Hence, a solvent may not only solvate the initial reagents and the initial state, but also take active part in its formation [6]. Such consideration may be performed using linear free energy relationships (LFER). Numerical accuracy of the description will depend on adequacy of a formal solvation model which forms the basis of corresponded LFE equation. At present, Koppel-Palm [5] and Kamlet-Taft [7] models are the most widespread. Corresponded reviews of various models are discussed in [8]. However, it should be remembered that these approaches are not the final dogma and are permanently changed and modified.
