ABSTRACT
I. Introduction ................................................................................................ 115 II. Insulin delivery as a model implant pump system............................. 117
A. Peristaltic pumps...........................................................................120 B. Fluorocarbon propellant-driven pumps....................................122 C. Osmotic pumps .............................................................................124 D. Miniosmotic pumps: systemic delivery ....................................125 E. Miniosmotic pumps: local delivery ...........................................126 F. Miniosmotic pumps: patterned delivery...................................127 G. Positive-displacement pumps .....................................................127 H. Controlled-release micropump ...................................................128 I. Other devices .................................................................................130
III. Implants for contraception .......................................................................130 A. Biodegradable ................................................................................130 B. Nonbiodegradable.........................................................................131
