ABSTRACT

Toxicity is the property or properties of a material that produces a harmful effect upon a biological system. A toxicant is the material that produces this biological effect. The majority of the chemicals discussed in this text are of man-made or anthropogenic origin. This is not to deny that extremely toxic materials are produced by biological systems; venom, botulinum endotoxin, and some of the fungal aflatoxins are extremely potent materials. However, compounds that are derived from natural sources are produced in low amounts. Anthropogenically derived compounds can be produced in millions of pounds per year.