ABSTRACT

Introduction Amantadine hydrochloride (AMD), Scheme 1, is an antiviral agent used against infection with inuenza type A virus and to ameliorate symptoms when administered during the early stages of infection as well as in the management of herpes zoster [1]. It has mild anti-Parkinsonism activity and thus it has been used in the management of Parkinsonism, mainly in the early disease stage and when the symptoms are mild. AMD is usually given by mouth as the hydrochloride salt [2].