Noninvasive imaging techniques are emerging into the forefront of medical diagnostics and treatment monitoring. Both near-and mid-infrared imaging techniques have provided invaluable information in the clinical setting. Most in vivo biomedical applications of functional imaging use light in the nearinfrared spectrum. e main advantage of the interaction of near-infrared light with tissue is increased penetration: light with wavelengths between 700 and 1100 nm passes through skin and other tissues better than visible light.