ABSTRACT
Nanotechnology provides an important new set of tools for the diagnosis and treatment of ocular diseases, a concept that has been reviewed previously.1-4 Nanoparticles include colloidal carrier systems that can improve the ef›cacy of drug delivery by overcoming diffusion barriers, permitting reduced dosing
13.1 Introduction .................................................................................................. 259 13.2 Nanovesicles ................................................................................................. 262
13.2.1 Liposomes, Niosomes, and Discomes .............................................. 262 13.3 Nanoparticles ................................................................................................ 262
13.3.1 Chitosan ............................................................................................264 13.3.2 Collagen ............................................................................................265 13.3.3 Poly(Lactic-Co-Glycolic Acid) .........................................................265 13.3.4 Nanoceria ..........................................................................................265 13.3.5 Dendrimers .......................................................................................266 13.3.6 CS-g-(PEI-b-mPEG) .........................................................................268
13.4 Nonvirus-Mediated Gene Delivery ..............................................................269 13.5 Virus-Mediated Gene Delivery .................................................................... 270
