ABSTRACT

Sulfated glycosaminoglycans (GAGs) such as heparin and heparan sulfate (HS) are linear glycans consisting of 1,4-linked uronic acid and glucosamine (Figure 11.1) and encompassing varying degrees of sulfation (Gandhi and Mancera 2008). The HS and

11.1 Introduction .................................................................................................. 259 11.2 Heparin/HS Mimetics as Anticoagulants .....................................................264