ABSTRACT

Two datasets will be analyzed in this chapter. The first dataset shown in Table 6.1 originates from a clinical trial in which lung cancer patients were randomized to receive two different kinds of chemotherapy (sequential therapy and alternating therapy). The outcome was classified into one of four categories: progressive disease, no change, partial remission, or complete remission. The data were published in Holtbrugge and Schumacher (1991) and also appear in Hand et al. (1994). The central question is whether there is any evidence of a difference in the outcomes achieved by the two types of therapy.