ABSTRACT

Appropriate sexual development at puberty and the cyclical processes of ovulation and menstruation involve a complex interaction of endocrine and target organs. Gonadotrophinreleasing hormones (GnRH) regulate the release of the gonadotrophins luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary gland. LH and FSH promote maturation of ova and secretion of oestrogen and progesterone from the ovaries.