ABSTRACT
The neuroleptic malignant syndrome is a rare and potentially
fatal disorder characterized, in its full expression, by the
tetrad of delirium, rigidity, fever, and autonomic instability,
which occurs secondary to an abrupt diminution of dopa-
minergic tone, due to either the use of a dopamine-blocking
agent, such as an antipsychotic, or, much less commonly, the
discontinuation of a dopaminergic agent, such as levodopa.
