ABSTRACT

Of the approximately 600 lymph nodes in the body, those in

the head and neck, axillary and inguinal regions are

potentially palpable. With no definite size criteria for what

constitutes enlargement or lymphadenopathy it has been

recommended that lymph nodes outside the inguinal area

present for longer than 1 month and over 1 1 cm in size without an obvious diagnosis require further investigation

(Habermann and Steensma 2000). In relation to sarcoidosis,

the large multicenter ACCESS study (A Case Control Etiologic

Study of Sarcoidosis) standardized an assessment tool

designed to define different organ involvement (Judson

et al. 1999). Definite involvement was confirmed if a biopsy

from the organ showed non-caseating granuloma without any

other cause being identified. Criteria for other organ involve-

ment in patients with biopsy-confirmed sarcoidosis were

based on clinical criteria and classified as definite, probable

and possible. The criteria for probable extrathoracic lymph

node involvement in a biopsy-confirmed sarcoidosis case was

defined as a new palpable lymph node above the waist and/or

lymph nodes 2 cm on CT scan. Possible involvement was defined as new palpable femoral lymph node(s).