ABSTRACT

The clinical course of sarcoidosis is often prolonged and may

be preceded by a varying period in which granulomatous

changes are present in various organs without causing

symptoms. It is also certain that some individuals go through

the entire course of sarcoidosis to spontaneous resolution

without symptoms, or with only trivial ones, although

granulomas, if sought, would be found in involved organs.

Thus it is to be expected that a proportion of patients will

show evidence of some other disease during the course of

known sarcoidosis; and that also during the investigation of

patients found to be suffering from some other disease,

evidence of previously unsuspected sarcoidosis will be found

occasionally.