ABSTRACT
The clinical manifestations of sarcoidosis vary from asymp-
tomatic disease to inflammation within a single organ or
multiple organs, often causing relatively non-specific symp-
toms and signs. A diagnosis of sarcoidosis may therefore need
to be considered in a range of clinical scenarios, many of
which have infectious disease as their differential diagnosis.
Infectious diseases also commonly cause granulomas so may
have a histological resemblance to sarcoid. Sarcoidosis can
also co-exist with infectious diseases, and cases of concomi-
tant infection and sarcoid have led to the suggestion that in
some cases sarcoidosis has been caused by infection.
