ABSTRACT
Although a great many research questions remain unan-
swered, the key issues for several decades have been the lack
of a robust etiologic model in sarcoidosis and lack of a
validated investigation and management algorithm for
pulmonary sarcoidosis, which remains the most prevalent
form of major organ involvement. Better understanding of
the etiology would cast light on many other aspects of
pathogenesis. Similarly, more accurate staging of pulmonary
disease and the development of more effective treatments
would have immediate relevance to the investigation and
management of other less prevalent patterns of major organ
involvement.
