ABSTRACT
Surgical resection is a prerequisite for long-term control but is only feasible in about 20 per cent of patients, of whom only 30 per cent will actually have an adequate R0 resection margin of 1 mm. Surgery can only be considered if there is no evidence of metastatic disease (commonly in the liver or peritoneum), no involvement of the coeliac, hepatic or superior mesenteric arteries, no obstruction of the confluence of the superior mesenteric and portal veins, and minimal portal vein involvement (180° involvement over 1 cm). The general PS of the patient must be good.
