ABSTRACT
The finding of ambiguous external genitalia must be managed sensitively and tactfully, as assignment of the wrong sex to a child will have long-term implications both for the child and the family. Once the diagnosis is made, the parents must be informed of the uncertainty. An important step must be to exclude CAH of the salt-losing type, as failure to recognise this may be associated with mortality. This is excluded by serum measurement of U&Es and various adrenal hormones (e.g. urinary 17 ketosteroids or serum 17α-hydroxyprogesterone).
