ABSTRACT
A 28-year-old lady who is 12 weeks’ gestation in her first pregnancy presents to her GP with a painless 2 cm lump in her right breast. She is seen by a specialist surgeon who makes the diagnosis of infiltrative ductal carcinoma on biopsy. The immunohistology of the biopsy demonstrates an oestrogen receptor-positive status. E With the finding of an infiltrative ductal carcinoma there is a significant chance
that the patient will require some form of adjuvant therapy after surgery. Therefore if chemotherapy is required in the first trimester of pregnancy, termination of pregnancy should be proposed owing to the possible teratogenic effects. If, however, the patient wishes to continue with the pregnancy, adjuvant therapy should be delayed until the second trimester.
